An overview of the Space Transportation System is presented in which aspects of the program operations are discussed. The various mission preparation and prelaunch operations are described including astronaut selection and training, Space Shuttle processing, Space Shuttle integration and rollout, Complex 39 launch pad facilities, and Space Shuttle cargo processing. Also, launch and flight operations and space tracking and data acquisition are described along with the mission control and payload operations control center. In addition, landing, postlanding, and solid rocket booster retrieval operations are summarized. Space Shuttle program management is described and Space Shuttle mission summaries and chronologies are presented. A glossary of acronyms and abbreviations are provided.